Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | EYA2 | O00167 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879133 | 1.00 | NPC1 (0.68) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL4878014 | 0.84 | NPC1 (0.59) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL4878016 | 0.84 | NPC1 (0.59) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL1026284 | 0.83 | RAB9A (0.77) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL27178156 | 0.81 | NPC1 (1.00) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL27178161 | 0.81 | NPC1 (1.00) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL30826084 | 0.81 | NPC1 (1.00) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL4888895 | 0.81 | CYP1A2 (0.64) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL4888888 | 0.81 | CYP1A2 (0.64) | NPC1RAB9AAGTR1OPRK1MAPT | |
| SCHEMBL5716401 | 0.80 | RAB9A (0.47) | NPC1RAB9AAGTR1OPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | NPC1 2644/4885RAB9A 3811/4885AGTR1 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.