SCHEMBL4879238

SCHEMBL4879238

CC(C)c1cccc(C(C)C)c1NS(N)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
POLB P06746 1/20 0.43
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
ACHE P22303 1/20 0.42
NLRP3 Q96P20 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11234113 0.82 L3MBTL1 (0.63) L3MBTL1LMNAKMT2ASMN1; SMN2POLB
SCHEMBL27182555 0.78 L3MBTL1 (0.46) L3MBTL1LMNAKMT2ASMN1; SMN2POLB
SCHEMBL12462804 0.77 KMT2A (0.53) L3MBTL1LMNAKMT2ASMN1; SMN2CA1
SCHEMBL23674205 0.76 L3MBTL1 (0.43) L3MBTL1LMNAKMT2ASMN1; SMN2POLB
SCHEMBL11435374 0.76 L3MBTL1 (0.43) L3MBTL1LMNAKMT2ASMN1; SMN2POLB
SCHEMBL9164476 0.74 NLRP3 (0.67) L3MBTL1LMNAKMT2ASMN1; SMN2POLB
SCHEMBL7080904 0.74 LMNA (0.43) LMNAKMT2ASMN1; SMN2
SCHEMBL2416593 0.73 L3MBTL1 (0.45) L3MBTL1POLBCA1CA2CA12
SCHEMBL9059808 0.73 NLRP3 (0.47) L3MBTL1LMNAKMT2ASMN1; SMN2POLB
SCHEMBL9386678 0.73 NLRP3 (0.47) NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080096922-A1 Novel Sulfonamide derivative DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2008-04-24 US disclosed
EP-1736467-A1 NOVEL SULFONAMIDE DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2006-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096922-A1 Novel Sulfonamide derivative NR4A1, NR4A2, NR4A3 L3MBTL1 3484/4885LMNA 3670/4885KMT2A 1132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.