Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512024 | 0.83 | CA1 (0.55) | CA1CA2PTGS2PTGS1TNFRSF1A | |
| SCHEMBL22360314 | 0.82 | CA1 (0.64) | CA1CA2PTGS2PTGS1TNFRSF1A | |
| SCHEMBL996403 | 0.77 | CA2 (0.63) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL6672713 | 0.75 | CA1 (0.55) | CA1CA2PTGS2PTGS1TNFRSF1A | |
| SCHEMBL4457970 | 0.74 | PTGS2 (0.44) | CA1CA2PTGS2PTGS1TNFRSF1A | |
| SCHEMBL5857102 | 0.73 | ALDH1A1 (0.52) | CA1CA2PTGS2PTGS1TNFRSF1A | |
| SCHEMBL2947022 | 0.73 | PTGS2 (0.47) | CA1CA2PTGS2PTGS1TNFRSF1A | |
| SCHEMBL1304840 | 0.72 | PTGS2 (0.43) | CA1CA2PTGS2PTGS1TNFRSF1A | |
| SCHEMBL14598537 | 0.72 | HPN (0.57) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL1305157 | 0.72 | PTGS2 (0.43) | CA1CA2PTGS2PTGS1TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125556-A1 | Copolymerizing two norbornene monomers, one having a pendant trimethylsilyl or timethylsilylmethyl group, and the other having optional pendant halogen or alkyl groups in the presence of a palladium-based multicomponent catalyst containing palladium, phosphorus, ionic boron and ionic aluminum compounds | JSR CORPORATION (JP) | 2008-05-29 | — | — | US | disclosed |