Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502266 | 0.92 | ALDH1A1 (0.42) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL30925599 | 0.90 | CA1 (0.46) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL19019980 | 0.89 | TNFRSF1A (0.46) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL6251712 | 0.85 | TNFRSF1A (0.42) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL14542318 | 0.84 | PTGS2 (0.46) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL1305157 | 0.84 | PTGS2 (0.43) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL1304840 | 0.84 | PTGS2 (0.43) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL21150370 | 0.83 | PTGS2 (0.42) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL459830 | 0.83 | PTGS2 (0.42) | PTGS2PTGS1ALDH1A1TDP1TSHR | |
| SCHEMBL6248683 | 0.81 | PTGS2 (0.45) | PTGS2PTGS1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110309304-A1 | LUMINESCENT SILVER COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-7569735-B2 | Reducing esters or lactones with hydrogen gas in presence of ruthenium catalyst; high yield and high catalytic efficiency under an industrially advantageous condition of relatively low hydrogen pressure and low reaction temperature | TAKASAGO INTERNATIONAL (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20080228012-A1 | Reducing esters or lactones with hydrogen gas in presence of ruthenium catalyst; high yield and high catalytic efficiency under an industrially advantageous condition of relatively low hydrogen pressure and low reaction temperature | TAKASAGO INTERNATIONAL CORPORATION | 2008-09-18 | — | — | US | disclosed |
| EP-1970360-A1 | Method for producing alcohols | Takasago International Corporation (JP) | 2008-09-17 | — | — | EP | disclosed |
| EP-0300772-B1 | Catalyst for polymerization of conjugated diene and process for producing conjugated diene polymer | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-4954125-A | COORDINATION CATALYST CONTAINING COBALT COMPOUND, ORGANIC PHOSPHINE COMPOUND, AND ORGANOALUMINUM COMPOUND | JAPAN SYNTHETIC RUBBER COMPANY, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0300772-A1 | Catalyst for polymerization of conjugated diene and process for producing conjugated diene polymer | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080228012-A1 | Reducing esters or lactones with hydrogen gas in presence of ruthenium catalyst; high yield and high catalytic efficiency under an industrially advantageous condition of relatively low hydrogen pressure and low reaction temperature | LPXN, LIPE, MLX | PTGS2 532/4885PTGS1 190/4885ALDH1A1 1512/4885 |
| US-20110309304-A1 | LUMINESCENT SILVER COMPLEX | SOD1, AS3MT, GLO1 | PTGS2 3571/4885PTGS1 3980/4885ALDH1A1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.