Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770058 | 0.88 | ALDH1A1 (0.48) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL11688996 | 0.82 | CACNA1D (0.48) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL11689003 | 0.82 | CACNA1D (0.48) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL28318011 | 0.82 | ADORA3 (0.49) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL4880853 | 0.80 | ABCC4 (0.47) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL10516391 | 0.79 | ALDH1A1 (0.51) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL5414545 | 0.79 | ALDH1A1 (0.45) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL5414539 | 0.79 | ALDH1A1 (0.45) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL10516412 | 0.79 | ALDH1A1 (0.51) | CACNA1CALDH1A1LMNAADORA3CACNA1F | |
| SCHEMBL3142647 | 0.78 | KDM4E (0.52) | CACNA1CALDH1A1LMNAADORA3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080095841-A1 | Pharmaceutical Composition, Method for Producing the Same, and Method for Stabilizing Dihydropyridine Compound in the Pharmaceutical Composition | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1813274-A1 | MEDICINAL COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND METHOD OF STABILIZING DIHYDROPYRIDINE COMPOUND IN MEDICINAL COMPOSITION | Eisai R&D Management Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |