Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414545 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL4880853 | 0.90 | ABCC4 (0.47) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL28318011 | 0.82 | ADORA3 (0.49) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL10516391 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL10516412 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL28770058 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL11007311 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL11009925 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTADORA3CACNA1F | |
| SCHEMBL5396699 | 0.79 | CYP1A2 (0.48) | MAPTADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL5396705 | 0.79 | CYP1A2 (0.48) | MAPTADORA3CACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |