Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907784 | 0.85 | NQO1 (0.52) | NQO1MAPTTSHRTDP1TP53 | |
| SCHEMBL17046377 | 0.83 | MAPT (0.41) | MAPTTP53KMT2ALTA4HMEN1 | |
| SCHEMBL16954559 | 0.81 | KMT2A (0.46) | MAPTTSHRTDP1CYP3A4KMT2A | |
| SCHEMBL1547677 | 0.78 | MAPT (0.54) | NQO1MAPTTSHRTDP1TP53 | |
| SCHEMBL3780893 | 0.78 | NQO1 (0.50) | NQO1MAPTTSHRTDP1TP53 | |
| SCHEMBL9321564 | 0.78 | NR5A1 (0.46) | TSHRTP53KMT2ALTA4HNPC1 | |
| SCHEMBL499727 | 0.77 | ESR1 (0.47) | NQO1MAPTTSHRTDP1TP53 | |
| SCHEMBL5740806 | 0.77 | NQO1 (0.44) | NQO1MAPTTSHRTDP1TP53 | |
| SCHEMBL16952562 | 0.77 | NQO1 (0.39) | NQO1MAPTTSHRTDP1TP53 | |
| SCHEMBL16951169 | 0.77 | KDM1A (0.36) | MAPTTSHRTDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642918-B | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | claimed |
| CN-110642918-A | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2020-01-03 | — | — | CN | claimed |
| US-10029992-B2 | Diaminotriazine compounds and their use as herbicides | BASF SE (DE) | 2018-07-24 | — | — | US | claimed |
| EP-3134391-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-03-01 | — | — | EP | claimed |
| US-20170044114-A1 | Diaminotriazine compounds and their use as herbicides | BASF SE (DE) | 2017-02-16 | — | — | US | claimed |
| WO-2015162166-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2015-10-29 | — | — | WO | claimed |
| US-20230150931-A1 | FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING | NOVIUS THERAPEUTICS, LLC (US) | 2023-05-18 | — | — | US | disclosed |
| EP-3544962-B1 | DIAMINOTRIAZINE COMPOUNDS | BASF SE (DE) | 2021-07-28 | — | — | EP | disclosed |
| CN-110642918-B | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | disclosed |
| US-20200383329-A1 | DIAMINOTRIAZINE COMPOUNDS | BASF SE (DE) | 2020-12-10 | — | — | US | disclosed |
| CN-110642918-A | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2020-01-03 | — | — | CN | disclosed |
| EP-3544962-A1 | DIAMINOTRIAZINE COMPOUNDS | BASF SE (DE) | 2019-10-02 | — | — | EP | disclosed |
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-3134391-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-20170044114-A1 | Diaminotriazine compounds and their use as herbicides | BASF SE (DE) | 2017-02-16 | — | — | US | disclosed |
| WO-2015162166-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2015-10-29 | — | — | WO | disclosed |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-20080293939-A1 | QUINAZOLINONE DERIVATIVES USEFUL AS ANTI-HYPERALGESIC AGENTS | CULSHAW ANDREW JAMES | 2008-11-27 | — | — | US | disclosed |
| US-20060154942-A1 | Quinazolinone derivatives useful as anti-hyperalgesic agents | CULSHAW ANDREW J | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293939-A1 | QUINAZOLINONE DERIVATIVES USEFUL AS ANTI-HYPERALGESIC AGENTS | OPRK1, OPRL1, TRPV1 | NQO1 171/4885MAPT 4614/4885TSHR 2413/4885 |
| US-20230150931-A1 | FABP4/5 INHIBITORS, METHODS OF USE AND METHODS OF MAKING | FABP5, FABP1, FABP4 | NQO1 1001/4885MAPT 3579/4885TSHR 3440/4885 |
| US-10029992-B2 | Diaminotriazine compounds and their use as herbicides | NR4A3, CBR3, RCOR3 | NQO1 549/4885MAPT 4632/4885TSHR 750/4885 |
| US-20200383329-A1 | DIAMINOTRIAZINE COMPOUNDS | DDT, DPM1, AOC1 | NQO1 65/4885MAPT 924/4885TSHR 2414/4885 |
| US-20060154942-A1 | Quinazolinone derivatives useful as anti-hyperalgesic agents | OPRK1, OPRL1, TRPV1 | NQO1 171/4885MAPT 4614/4885TSHR 2413/4885 |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | CYP4X1, CBR3, PAOX | NQO1 1187/4885MAPT 4724/4885TSHR 1336/4885 |
| US-20170044114-A1 | Diaminotriazine compounds and their use as herbicides | NR4A3, CBR3, RCOR3 | NQO1 569/4885MAPT 4623/4885TSHR 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.