Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45405 | 1.00 | USP2 (0.49) | USP2MAPTTHRBALOX15HIF1A | |
| SCHEMBL10608422 | 0.91 | SLC7A5 (0.50) | USP2MAPTTHRBALOX15HIF1A | |
| SCHEMBL296690 | 0.91 | SLC7A5 (0.50) | USP2MAPTTHRBALOX15HIF1A | |
| SCHEMBL38374 | 0.91 | SLC7A5 (0.50) | USP2MAPTTHRBALOX15HIF1A | |
| Bromide SCHEMBL10477399 | 0.90 | SLC7A5 (0.49) | USP2MAPTTHRBALOX15HIF1A | |
| Bromide SCHEMBL10477401 | 0.90 | SLC7A5 (0.49) | USP2MAPTTHRBALOX15HIF1A | |
| Hydrochloric Acid SCHEMBL10477430 | 0.90 | SLC7A5 (0.49) | USP2MAPTTHRBALOX15HIF1A | |
| Hydrochloric Acid SCHEMBL10421601 | 0.90 | SLC7A5 (0.49) | USP2MAPTTHRBALOX15HIF1A | |
| SCHEMBL13957561 | 0.84 | USP2 (0.46) | USP2MAPTTHRBALOX15HIF1A | |
| SCHEMBL29141120 | 0.84 | USP2 (0.46) | USP2MAPTTHRBALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021981-A2 | METHODS FOR THE PREPARATION OF β-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-03-18 | — | — | WO | claimed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| CN-104225574-B | METHODS FOR PREVENTING MITOCHONDRIAL PERMEABILITY TRANSITION | 科内尔研究基金会 | 2017-01-11 | — | — | CN | disclosed |
| CN-106163537-A | Cuorin targeting peptides suppression amyloid beta oligomer toxicity | 康奈尔大学 | 2016-11-23 | — | — | CN | disclosed |
| CN-106102760-A | Aromatic-cationic peptides is for treating the purposes of the mitochondria dysfunction of cholesterol induction | 康奈尔大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-106039282-A | AROMATIC-CATIONIC PEPTIDES AND USES OF SAME | 康奈尔大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-105879008-A | METHODS FOR THE PREVENTION OR TREATMENT OF NO-REFLOW FOLLOWING ISCHEMIA/REPERFUSION INJURY | 康德生物医疗技术公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105579054-A | Methods of preventing or treating left ventricular remodeling | STEALTH PEPTIDES INT INC | 2016-05-11 | — | — | CN | disclosed |
| CN-105056206-A | Methods and compositions for preventing or treating ophthalmic conditions | STEALTH PEPTIDES INT INC | 2015-11-18 | — | — | CN | disclosed |
| CN-105031605-A | Methods for preventing or treating metabolic syndrome | UNIV CORNELL | 2015-11-11 | — | — | CN | disclosed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | disclosed |
| US-20020177725-A1 | Peptide inhibitors of hepatitis C virus NS3 protein | BRISTOL-MYERS SQUIBB COMPANY (FORMERLY D/B/A DUPONT PHARMACEUTICALS COMPANY) | 2002-11-28 | — | — | US | disclosed |
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-05 | — | — | US | disclosed |
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-05-30 | — | — | US | disclosed |
| EP-1196436-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002424-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0787010-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012499-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | TMPRSS15, CTRC, CPN1 | USP2 319/4885MAPT 4425/4885THRB 4356/4885 |
| US-20020177725-A1 | Peptide inhibitors of hepatitis C virus NS3 protein | VIP, PRSS1, SERPINB1 | USP2 867/4885MAPT 3585/4885THRB 4194/4885 |
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | CES1, CYP51A1, SPINT2 | USP2 633/4885MAPT 3370/4885THRB 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.