Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.69 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877793 | 0.91 | OPRM1 (0.72) | OPRM1OPRD1OPRK1OPRL1CYP3A4 | |
| SCHEMBL5476317 | 0.88 | OPRM1 (0.69) | OPRM1OPRD1OPRK1OPRL1CYP3A4 | |
| SCHEMBL4871634 | 0.84 | OPRM1 (0.60) | OPRM1OPRD1OPRK1OPRL1CYP3A4 | |
| SCHEMBL3507379 | 0.82 | LMNA (0.54) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL2701083 | 0.81 | SIGMAR1 (0.57) | OPRM1CYP2D6MAPTALDH1A1LMNA | |
| SCHEMBL10002406 | 0.80 | LMNA (0.58) | OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL4878651 | 0.79 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1CYP3A4 | |
| SCHEMBL5668891 | 0.79 | LMNA (0.65) | OPRM1OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL5476169 | 0.78 | SOAT1 (0.55) | MAPT | |
| SCHEMBL11865726 | 0.76 | PDE4A (0.55) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | OPRM1 1290/4885OPRD1 628/4885OPRK1 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.