Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.50 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31259768 | 0.76 | EPHX2 (0.60) | KDM4ECYP1A2TSHRMEN1KMT2A | |
| SCHEMBL8536908 | 0.75 | NPC1 (0.72) | SLC6A9SLC6A5CYP27B1CYP24A1GPR139 | |
| Hydrochloric Acid SCHEMBL4890327 | 0.73 | ALDH1A1 (0.46) | KDM4ECYP1A2TSHRMEN1KMT2A | |
| SCHEMBL5226231 | 0.73 | HDAC6 (0.72) | CYP1A2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL23014479 | 0.72 | KMT2A (0.73) | SLC6A9SLC6A5GPR139GAACYP1A2 | |
| Bromide SCHEMBL6239893 | 0.72 | MAPT (0.54) | TSHRMEN1KMT2AMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4887328 | 0.72 | ALDH1A1 (0.42) | KDM4EGAACYP1A2TSHRMEN1 | |
| SCHEMBL4618812 | 0.72 | EPHX2 (0.79) | SLC6A9SLC6A5GPR139KDM4EGAA | |
| Hydrochloric Acid SCHEMBL16909942 | 0.72 | HTT (0.51) | KDM4EGAACYP1A2TSHRNFKB1 | |
| SCHEMBL23014135 | 0.72 | MEN1 (0.65) | SLC6A9SLC6A5GPR139KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976388-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2008-10-08 | — | — | EP | claimed |
| US-20080199502-A1 | Antimicrobial Solution Comprising a Metallic Salt and a Surfactant | CTT GROUP INC. (CA) | 2008-08-21 | — | — | US | claimed |
| WO-2006105669-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2006-10-12 | — | — | WO | claimed |
| US-20150201622-A1 | NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | CTT GROUP INC (CA) | 2015-07-23 | — | — | US | disclosed |
| EP-1976388-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2008-10-08 | — | — | EP | disclosed |
| US-20080199502-A1 | Antimicrobial Solution Comprising a Metallic Salt and a Surfactant | CTT GROUP INC. (CA) | 2008-08-21 | — | — | US | disclosed |
| WO-2006105669-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2006-10-12 | — | — | WO | disclosed |