Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4890327

O=C(CCl)NC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Cl-]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.46
HTT P42858 7/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
MITF O75030 2/20 0.46
NCOA1 Q15788 1/20 0.45
NCOA3 Q9Y6Q9 1/20 0.45
LMNA P02545 4/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 2/20 0.39
KDM4E B2RXH2 1/20 0.39
RNF4 P78317 1/20 0.39
HIF1A Q16665 2/20 0.39
MAPK1 P28482 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4862612 0.78 ALDH1A1 (0.51) ALDH1A1HTTSMN1; SMN2NCOA1NCOA3
Hydrochloric Acid SCHEMBL4887328 0.77 ALDH1A1 (0.42) ALDH1A1HTTSMN1; SMN2RAB9ANPC1
SCHEMBL15671577 0.76 ALDH1A1 (0.67) ALDH1A1HTTSMN1; SMN2NCOA1NCOA3
Hydrochloric Acid SCHEMBL11422525 0.75 TSHR (0.43) ALDH1A1HTTSMN1; SMN2RAB9ALMNA
SCHEMBL4855491 0.75 BCAT2 (0.64) ALDH1A1HTTSMN1; SMN2RAB9ANPC1
Hydrochloric Acid SCHEMBL4888706 0.74 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2RAB9ANPC1CYP1A2
Hydrochloric Acid SCHEMBL4881121 0.74 POLB (0.49) ALDH1A1HTTSMN1; SMN2RAB9ANPC1
SCHEMBL11200675 0.74 ALDH1A1 (0.47) ALDH1A1HTTSMN1; SMN2RAB9ANPC1
Hydrochloric Acid SCHEMBL4881143 0.73 SLC6A9 (0.51) ALDH1A1RAB9ANPC1LMNACYP1A2
SCHEMBL7090783 0.73 ALDH1A1 (0.51) ALDH1A1HTTSMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP claimed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US claimed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO claimed
US-20150201622-A1 NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF CTT GROUP INC (CA) 2015-07-23 US disclosed
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP disclosed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US disclosed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO disclosed