Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14145112 | 0.84 | CYP3A4 (0.40) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL14577502 | 0.74 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL4883157 | 0.72 | POLB (0.41) | ALDH1A1LMNAMAPTRAB9ATSHR | |
| SCHEMBL4613475 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNACYP2C19MMP8GAA | |
| SCHEMBL29115627 | 0.69 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL29115625 | 0.69 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL9408553 | 0.67 | HTT (0.40) | ALDH1A1LMNAMMP8GAA | |
| SCHEMBL9358305 | 0.67 | HTT (0.40) | ALDH1A1LMNAMMP8GAA | |
| SCHEMBL27667334 | 0.67 | MMP8 (0.35) | ALDH1A1LMNAMAPTMMP8GAA | |
| SCHEMBL13418944 | 0.66 | L3MBTL1 (0.43) | ALDH1A1LMNAMAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2008-08-07 | — | — | US | disclosed |
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2008-08-07 | — | — | US | disclosed |
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC1, PGRMC2 | ALDH1A1 1387/4885LMNA 1722/4885MAPT 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.