Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881785 | 0.80 | MEN1 (0.69) | ALDH1A1SMN1; SMN2USP2HTTLMNA | |
| SCHEMBL4880521 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2USP2HTTLMNA | |
| SCHEMBL4882943 | 0.72 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2USP2HTTLMNA | |
| SCHEMBL19721050 | 0.68 | PARP1 (0.42) | ALDH1A1SMN1; SMN2USP2HTTLMNA | |
| SCHEMBL26789504 | 0.55 | MAPT (0.40) | ALDH1A1SMN1; SMN2HTTMAPTTHRB | |
| SCHEMBL17251487 | 0.53 | LMNA (0.49) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL3295899 | 0.53 | ADORA3 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTTSHR | |
| SCHEMBL24026375 | 0.52 | PARP1 (0.67) | ALDH1A1SMN1; SMN2USP2HTTLMNA | |
| SCHEMBL9892899 | 0.52 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2MAPTCYP1A2MEN1 | |
| SCHEMBL26789513 | 0.52 | LMNA (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249154-A1 | Preventive and/or Therapeutic Agent For Disease In Which Mitochondrial Benzodiazephine Receptor Participates | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-10-09 | — | — | US | disclosed |
| EP-1698335-A1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR DISEASE IN WHICH MITOCHONDRIAL BENZODIAZEPINE RECEPTOR PARTICIPATES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249154-A1 | Preventive and/or Therapeutic Agent For Disease In Which Mitochondrial Benzodiazephine Receptor Participates | MTNR1A, GSR, NLN | ALDH1A1 1371/4885SMN1; SMN2 1071/4885USP2 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.