Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882274 | 1.00 | MAPT (0.59) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4884882 | 0.87 | KCNK3 (0.54) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4884887 | 0.87 | KCNK3 (0.54) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4878977 | 0.86 | MAPT (0.59) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4878983 | 0.86 | MAPT (0.59) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5715919 | 0.85 | NPC1 (0.53) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5715915 | 0.85 | NPC1 (0.53) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4886121 | 0.85 | KMT2A (0.48) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4886123 | 0.85 | KMT2A (0.48) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4890021 | 0.84 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
| EP-1725227-A1 | USE OF NEW LIPOXYGENASE INHIBITORS | Biolipox AB (SE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005084656-A1 | USE OF NEW LIPOXYGENASE INHIBITORS | BIOLIPOX AB (SE) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | MAPT 4603/4885SMN1; SMN2 3659/4885ALDH1A1 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.