SCHEMBL4882625

SCHEMBL4882625

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nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.37
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.33
MPI P34949 1/20 0.33
PGD P52209 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL624112 0.82 MPI (0.37) MPI
SCHEMBL419463 0.82 MPI (0.37) MPI
Lactic Acid SCHEMBL2582472 0.81 TP53 (0.37) MPI
Bicarbonate SCHEMBL8384988 0.80 MPI (0.36) MPI
Bicarbonate SCHEMBL8384375 0.80 MPI (0.36) MPI
SCHEMBL19951545 0.80 PDE4A (0.61) PDE4ATSHRHTTPGD
SCHEMBL1162410 0.80 PDE4A (0.61) PDE4ATSHRHTTPGD
SCHEMBL8937118 0.79 MPI (0.35) MPI
SCHEMBL424017 0.79 MPI (0.35) MPI
SCHEMBL6863025 0.79 MPI (0.35) MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631779-B Polyol esters and their use in processing halogenated vinyl polymers 济南金昌树新材料科技有限公司 2020-07-14 CN disclosed
US-8865229-B2 Marrubiin and composition for reducing snoring, package and method PURANOX MEDICAL B.V. (NL) 2014-10-21 US disclosed
US-20110305780-A1 Marrubiin and composition for reducing snoring, package and method PURANOX MEDICAL B.V. (NL) 2011-12-15 US disclosed
US-20080305192-A1 Marrubiin and Composition For Reducing Snoring, Package and Method PURANOX MEDICAL B.V. (NL) 2008-12-11 US disclosed
CN-1427013-A Self-viscous cationic or amphoteric free-radical polymer and their use in cosmetics OREAL (FR) 2003-07-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305192-A1 Marrubiin and Composition For Reducing Snoring, Package and Method NISCH, UTRN, MTPN PDE4A 217/4885TSHR 2388/4885HTT 2044/4885
US-20110305780-A1 Marrubiin and composition for reducing snoring, package and method NISCH, UTRN, MTPN PDE4A 172/4885TSHR 2744/4885HTT 2129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.