Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8384988 | 1.00 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL419463 | 0.98 | MPI (0.37) | MPIALDH1A1 | |
| SCHEMBL624112 | 0.98 | MPI (0.37) | MPIALDH1A1 | |
| SCHEMBL1607595 | 0.92 | MPI (0.38) | MPIALDH1A1 | |
| SCHEMBL1032576 | 0.83 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL215097 | 0.81 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL789905 | 0.81 | MPI (0.36) | MPI | |
| SCHEMBL2884877 | 0.81 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL426315 | 0.81 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL2354360 | 0.81 | MPI (0.36) | MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939091-A | INTRABUCCALLY DISSOLVING AND PARTIALLY DISSOLVING COMPRESSED TABLETS; THE TABLETS DELIVER AN ACTIVE INGREDIENT IN AN EASY CHEW FORM THAT QUICKLY DISINTEGRATES IN THE BUCCAL CAVITY | WARNER LAMBERT COMPANY (US) | 1999-08-17 | — | — | US | disclosed |