Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677786 | 0.84 | SLC7A5 (0.36) | ITGA4ITGB7KMT2AL3MBTL1LMNA | |
| SCHEMBL27829292 | 0.84 | SLC7A5 (0.36) | ITGA4ITGB7KMT2AL3MBTL1LMNA | |
| SCHEMBL1147247 | 0.83 | CASP1 (0.38) | KMT2AL3MBTL1IDO1TDO2LMNA | |
| SCHEMBL27829333 | 0.83 | HTT (0.37) | ITGA4ITGB7KMT2APOLBHTT | |
| SCHEMBL27477423 | 0.83 | IDO1 (0.39) | KMT2AIDO1TDO2SLC7A5 | |
| SCHEMBL27506659 | 0.83 | IDO1 (0.39) | KMT2AIDO1TDO2SLC7A5 | |
| SCHEMBL27584351 | 0.82 | AOC3 (0.40) | ITGA4ITGB7POLBKDM4EACHE | |
| SCHEMBL9451398 | 0.81 | PPARG (0.45) | ITGA4ITGB7MTNR1AMTNR1B | |
| SCHEMBL27487741 | 0.81 | ALDH1A1 (0.41) | KMT2AHTTKDM4ESLC7A5KIF11 | |
| SCHEMBL27677762 | 0.81 | LMNA (0.40) | POLBIDO1TDO2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262005-A1 | Uracil-Type Gonadotropin-Releasing Hormone Receptor Antagonists and Methods Related Thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| WO-2005113516-A1 | URACIL-TYPE GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262005-A1 | Uracil-Type Gonadotropin-Releasing Hormone Receptor Antagonists and Methods Related Thereto | GNRHR, FSHR, GHRHR | ITGA4 4638/4885ITGB7 4240/4885KMT2A 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.