SCHEMBL4883555

SCHEMBL4883555

Fc1ccc(Cc2noc(CCl)n2)cc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 5/20 0.46
KMT2A Q03164 4/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 3/20 0.45
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9670480 0.85 MAPT (0.58) TSHRMAPK1TDP1L3MBTL1KMT2A
SCHEMBL481007 0.83 MAPK1 (0.48) TSHRMAPK1TDP1L3MBTL1MAPT
SCHEMBL24264721 0.83 KMT2A (0.48) TSHRMAPK1TDP1L3MBTL1KMT2A
SCHEMBL11638729 0.83 MAPK1 (0.61) TSHRMAPK1TDP1L3MBTL1KMT2A
SCHEMBL5635245 0.80 L3MBTL1 (0.43) TSHRMAPK1TDP1L3MBTL1KMT2A
SCHEMBL23578233 0.80 TSHR (0.45) TSHRMAPK1TDP1L3MBTL1KMT2A
SCHEMBL20900122 0.79 L3MBTL1 (0.46) TSHRMAPK1TDP1L3MBTL1KMT2A
SCHEMBL23588090 0.78 TSHR (0.72) TSHRMAPK1TDP1POLBMAPT
SCHEMBL101986 0.77 L3MBTL1 (0.41) TSHRMAPK1TDP1L3MBTL1KMT2A
SCHEMBL23239259 0.77 TRPA1 (0.45) L3MBTL1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255202-A1 Phenylthioacetic Acid Derivatives and Use Thereof BAYER HEALTHCARE AG (DE) 2008-10-16 US disclosed
US-20080255202-A1 Phenylthioacetic Acid Derivatives and Use Thereof BAYER HEALTHCARE AG (DE) 2008-10-16 US disclosed
US-20080255202-A1 Phenylthioacetic Acid Derivatives and Use Thereof BAYER HEALTHCARE AG (DE) 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255202-A1 Phenylthioacetic Acid Derivatives and Use Thereof PAH, TST, MPST TSHR 1964/4885MAPK1 1814/4885TDP1 347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.