Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884399 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HPGDGLAMAPTMEN1 | |
| SCHEMBL9226526 | 0.80 | ALDH1A1 (0.77) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL5269218 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HPGDGLAMAPTTHRB | |
| SCHEMBL5269737 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HPGDGLAMAPTTHRB | |
| SCHEMBL820663 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HPGDGLAMAPTTHRB | |
| SCHEMBL24781206 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HPGDGLAMAPTTHRB | |
| SCHEMBL24781207 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HPGDGLAMAPTTHRB | |
| SCHEMBL9229590 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTTHRBMEN1 | |
| SCHEMBL28277817 | 0.72 | ALDH1A1 (0.83) | ALDH1A1HPGDGLAMAPTTHRB | |
| SCHEMBL19760402 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838659-B1 | PROCESS FOR PREPARATION OF N,N-DIISOPROPYL-3-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPYLAMINE | LEK PHARMACEUTICALS (SI) | 2015-07-15 | — | — | EP | disclosed |
| US-20080045602-A1 | Process for Preparation of 3-(2-Hydroxy-5Methylphenyl)-N, N-Disopropyl-3-Phenylpropylamine | LEK PHARMACEUTICALS, D.D. (SI) | 2008-02-21 | — | — | US | disclosed |
| EP-1838659-A1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-METHYLPHENYL)-N,N-DIISOPROPYL-3PHENYLPROPYLAMINE | LEK Pharmaceuticals D.D. (SI) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006066931-A1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-METHYLPHENYL)-N,N-DIISOPROPYL-3PHENYLPROPYLAMINE | LEK PHARMACEUTICALS D.D. (SI) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045602-A1 | Process for Preparation of 3-(2-Hydroxy-5Methylphenyl)-N, N-Disopropyl-3-Phenylpropylamine | SLC6A3, PNMT, PIR | ALDH1A1 1210/4885HPGD 584/4885GLA 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.