SCHEMBL820663

SCHEMBL820663

Cc1ccc2c(c1)C(c1ccccc1)CC(=O)O2

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.79
ALDH2 P05091 1/20 0.79
HPGD P15428 4/20 0.70
GAA P10253 2/20 0.70
HSD17B10 Q99714 1/20 0.70
GLA P06280 1/20 0.67
SIRT2 Q8IXJ6 5/20 0.64
MEN1 O00255 4/20 0.59
MAPT P10636 4/20 0.59
KMT2A Q03164 4/20 0.59
RECQL P46063 1/20 0.59
THRB P10828 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5269737 1.00 ALDH1A1 (0.79) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL5269218 1.00 ALDH1A1 (0.79) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL4878921 0.88 ALDH1A1 (1.00) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL725197 0.82 ALDH1A1 (0.70) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL9228116 0.82 ALDH1A1 (0.70) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL12856664 0.82 ALDH1A1 (0.70) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL580157 0.82 ALDH1A1 (0.73) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL579722 0.82 ALDH1A1 (0.65) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL9223130 0.81 ALDH1A1 (0.68) ALDH1A1ALDH2HPGDGAAHSD17B10
SCHEMBL14852665 0.81 ALDH1A1 (0.68) ALDH1A1ALDH2HPGDGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112433445-B Photosensitive resin composition for UV LED light source marking and dry film resist 福斯特(安吉)新材料有限公司 2023-12-26 CN claimed
CN-112433445-A Photosensitive resin composition for marking UV LED light source and dry film resist 福斯特(安吉)新材料有限公司 2021-03-02 CN claimed
EP-1701932-B1 TOLTERODINE, COMPOSITIONS AND USES THEREOF, AND PREPARATION OF THE SAME CIPLA LTD (IN) 2012-07-18 EP claimed
US-20110306792-A1 PROCESS FOR PREPARING TOLTERODINE AND THE L-TARTRATE THEREOF 2Y-CHEM, LTD. (CN) 2011-12-15 US claimed
CN-101087751-B Process for preparation of 3-(2-hydroxy-5-methylphenyl)-n,n-diisopropyl-3phenylpropylamine LEK PHARMACEUTICALS 2011-11-02 CN claimed
WO-2010092500-A2 A PROCESS FOR THE PREPARATION OF TOLTERODINE TARTRATE ALEMBIC LIMITED (IN) 2010-08-19 WO claimed
WO-2010046801-A2 A PROCESS FOR THE PREPARATION OF TOLTERODINE TARTRATE ALEMBIC LIMITED (IN) 2010-04-29 WO claimed
US-7538249-B2 Tolterodine, compositions and uses thereof, and preparation of the same CIPLA LIMITED (IN) 2009-05-26 US claimed
CN-101087751-A Process for preparation of 3-(2-hydroxy-5-methylphenyl)-n,n-diisopropyl-3phenylpropylamine LEK PHARMACEUTICALS (SI) 2007-12-12 CN claimed
US-20070142479-A1 Tolterodine, compositions and uses thereof, and preparation of the same CIPLA LIMITED (IN) 2007-06-21 US claimed
EP-1701932-A1 TOLTERODINE, COMPOSITIONS AND USES THEREOF, AND PREPARATION OF THE SAME Cipla Ltd. (IN) 2006-09-20 EP claimed
EP-1419135-A4 PROCESS FOR THE PREPARATION OF TOLTERODINE RANBAXY LAB LTD (IN) 2006-01-11 EP claimed
EP-1584621-A1 A process for the preparation of tolterodine and intermediates thereof Dipharma S.p.A. (IT) 2005-10-12 EP claimed
US-20050222437-A1 Process for the preparation of tolterodine and intermediates thereof DIPHARMA S.P.A. (IT) 2005-10-06 US claimed
WO-2005061432-A1 TOLTERODINE, COMPOSITIONS AND USES THEREOF, AND PREPARATION OF THE SAME CIPLA LIMITED (IN) 2005-07-07 WO claimed
CN-1571767-A Process for the preparation of tolterodine RANBAXY LAB LTD (IN) 2005-01-26 CN claimed
US-20040249211-A1 PROCESS FOR THE PREPARATION OF TOLTERODINE RANBAXY LABORATORIES LIMITED (IN) 2004-12-09 US claimed
US-6822119-B1 REACTING 3,4-DIHYDRO-6-METHYL-4-PHENYL-2H-BENZOPYRAN-2-ONE WITH DIMETHYL SULFATE USING PHASE TRANSFER CATALYST; DESTERIFICATION, REDUCTION, AMINATION, SULFONATION, DEPROTECTING, DECYCLIZATION, AND SALT FORMATION RANBAXY LABORATORIES LIMITED (IN) 2004-11-23 US claimed
EP-1419135-A1 PROCESS FOR THE PREPARATION OF TOLTERODINE RANBAXY LABORATORIES, LTD. (IN) 2004-05-19 EP claimed
WO-2003014060-A1 PROCESS FOR THE PREPARATION OF TOLTERODINE RANBAXY LABORATORIES LIMITED (IN) 2003-02-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110306792-A1 PROCESS FOR PREPARING TOLTERODINE AND THE L-TARTRATE THEREOF ACHE, QDPR, DDC ALDH1A1 1592/4885ALDH2 757/4885HPGD 1582/4885
US-20050222437-A1 Process for the preparation of tolterodine and intermediates thereof CYP2B6, UGT1A6, CYP2D6 ALDH1A1 1277/4885ALDH2 1890/4885HPGD 1820/4885
US-20040249211-A1 PROCESS FOR THE PREPARATION OF TOLTERODINE ADRB3, ADRA1B, ADRA2B ALDH1A1 1876/4885ALDH2 1887/4885HPGD 1531/4885
US-20070142479-A1 Tolterodine, compositions and uses thereof, and preparation of the same ADRB3, ADRB2, ADRB1 ALDH1A1 1558/4885ALDH2 1577/4885HPGD 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.