Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634844 | 0.81 | KDM4E (0.36) | FOLH1 | |
| SCHEMBL30203144 | 0.77 | POLB (0.32) | — | |
| Potassium Ion SCHEMBL4886117 | 0.77 | FOLH1 (0.35) | FOLH1 | |
| SCHEMBL3239940 | 0.76 | KDM4E (0.31) | FOLH1 | |
| SCHEMBL10090494 | 0.76 | FOLH1 (0.43) | FOLH1 | |
| SCHEMBL19462018 | 0.74 | FOLH1 (0.31) | FOLH1 | |
| SCHEMBL19064231 | 0.72 | FOLH1 (0.40) | FOLH1 | |
| SCHEMBL20150961 | 0.72 | FOLH1 (0.34) | FOLH1 | |
| SCHEMBL716120 | 0.72 | FOLH1 (0.47) | FOLH1 | |
| SCHEMBL20150964 | 0.72 | FOLH1 (0.47) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150268246-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC | 2015-09-24 | — | — | US | disclosed |
| US-20080076188-A1 | Luminescent compounds | SETA BIOMEDICALS, LLC | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076188-A1 | Luminescent compounds | REL, QRFPR, RCOR3 | FOLH1 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.