SCHEMBL4884623

SCHEMBL4884623

C=CCOC(C)(C=C)CCC=C(C)C

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.52
HIF1A Q16665 4/20 0.38
EPAS1 Q99814 4/20 0.38
TSHR P16473 1/20 0.33
GGPS1 O95749 1/20 0.33
FNTA P49354 1/20 0.30
FNTB P49356 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164899 0.84 ALOX15 (0.53) ALOX15HIF1AEPAS1TSHRGGPS1
SCHEMBL28452346 0.84 ALOX15 (0.53) ALOX15HIF1AEPAS1TSHRGGPS1
SCHEMBL159275 0.83 ALOX15 (0.58) ALOX15GGPS1FNTAFNTB
SCHEMBL28850310 0.82 ALOX15 (0.60) ALOX15GGPS1FNTAFNTB
SCHEMBL988359 0.81 ALOX15 (0.59) ALOX15HIF1AEPAS1TSHR
SCHEMBL29170184 0.81 ALOX15 (0.50) ALOX15HIF1AEPAS1TSHR
SCHEMBL454435 0.79 ALOX15 (0.57) ALOX15HIF1AEPAS1TSHR
SCHEMBL28480784 0.79 ALOX15 (0.57) ALOX15HIF1AEPAS1TSHR
SCHEMBL8160898 0.79 ALOX15 (0.57) ALOX15HIF1AEPAS1TSHR
SCHEMBL301116 0.79 ALOX15 (0.49) ALOX15HIF1AEPAS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110746277-B Pre-fragrance compounds 弗门尼舍有限公司 2023-06-09 CN disclosed
US-10752862-B2 Pro-fragrance compounds FIRMENICH SA (CH) 2020-08-25 US disclosed
EP-2994447-B1 PRO-FRAGRANCE COMPOUNDS FIRMENICH & CIE (CH) 2020-04-08 EP disclosed
CN-110746277-A Pro-fragrance compounds 弗门尼舍有限公司 2020-02-04 CN disclosed
US-20170283737-A1 PRO-FRAGRANCE COMPOUNDS FIRMENICH SA (CH) 2017-10-05 US disclosed
US-9718753-B2 Pro-fragrance compounds FIRMENICH SA (CH) 2017-08-01 US disclosed
US-20160122271-A1 PRO-FRAGRANCE COMPOUNDS FIRMENICH SA (CH) 2016-05-05 US disclosed
EP-2994447-A1 PRO-FRAGRANCE COMPOUNDS Firmenich SA (CH) 2016-03-16 EP disclosed
US-7413849-B2 Substituted benzene developing solvent for photopolymerizable printing plates NUPRO TECHNOLOGIES (US) 2008-08-19 US disclosed
US-20060057498-A1 Substituted benzene developing solvent for photopolymerizable printing plates EASTMAN KODAK COMPANY 2006-03-16 US disclosed
WO-2005047982-A1 TERPENE ETHER DEVELOPING SOLVENT FOR PHOTOPOLYMERIZABLE PRINTING PLATES NUPRO TECHLOLOGIES (US) 2005-05-26 WO disclosed
US-6897008-B1 Terpene ether developing solvent for photopolymerizable printing plates NUPRO TECHNOLOGIES, INC. (US) 2005-05-24 US disclosed
US-20050100823-A1 TERPENE ETHER DEVELOPING SOLVENT FOR PHOTOPOLYMERIZABLE PRINTING PLATES KODAK AMERICAS LTD. 2005-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10752862-B2 Pro-fragrance compounds ADH5, HRH1, C9 ALOX15 120/4885HIF1A 861/4885EPAS1 4211/4885
US-20160122271-A1 PRO-FRAGRANCE COMPOUNDS HRH1, ADH5, C9 ALOX15 219/4885HIF1A 930/4885EPAS1 4133/4885
US-20170283737-A1 PRO-FRAGRANCE COMPOUNDS ADH5, HRH1, C9 ALOX15 120/4885HIF1A 861/4885EPAS1 4211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.