Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 7/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 7/20 | 0.45 |
| ▸ | CHRM5 known ✓ | P08912 | 6/20 | 0.45 |
| ▸ | CHRM2 known ✓ | P08172 | 6/20 | 0.45 |
| ▸ | CHRM4 known ✓ | P08173 | 6/20 | 0.45 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705795 | 0.98 | CHRM5 (0.47) | GALR3GAARAB9ACHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL737407 | 0.96 | CHRM5 (0.48) | GALR3GAARAB9ACHRM1CHRM3 | |
| SCHEMBL1502491 | 0.85 | CHRM5 (0.37) | GALR3GAARAB9ACHRM1CHRM3 | |
| SCHEMBL28516066 | 0.81 | ALDH1A1 (0.48) | TSHRALDH1A1APEX1THRB | |
| SCHEMBL22245377 | 0.81 | CHRM5 (0.36) | GALR3GAARAB9ACHRM1CHRM3 | |
| Bromide SCHEMBL366432 | 0.80 | CHRM1 (0.63) | GALR3GAARAB9ACHRM1CHRM3 | |
| SCHEMBL3683081 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2ADRA1ALMNAMAPTBLM | |
| SCHEMBL15439901 | 0.79 | THRB (0.39) | CHRM1CHRM3CHRM2CHRNB2CHRNA4 | |
| SCHEMBL28274196 | 0.79 | BBOX1 (0.37) | GALR3GAARAB9ACHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL15954 | 0.78 | CHRM5 (0.65) | GALR3GAARAB9ACHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9093196-B2 | Conductive particles and method of preparing the same | NISSHINBO HOLDINGS, INC. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20080078977-A1 | CONDUCTIVE PARTICLES AND METHOD OF PREPARING THE SAME | NISSHINBO INDUSTRIES, INC. (JP) | 2008-04-03 | — | — | US | disclosed |