Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.33 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.33 |
| ▸ | CHRNA10 known ✓ | Q9GZZ6 | 1/20 | 0.33 |
| ▸ | CHRNA9 known ✓ | Q9UGM1 | 1/20 | 0.33 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.30 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275365 | 0.91 | BBOX1 (0.35) | BBOX1ACHEGALR3CHRM5CHRM1 | |
| SCHEMBL1502491 | 0.82 | CHRM5 (0.37) | BBOX1GALR3CHRM5CHRM1CHRM3 | |
| SCHEMBL7705795 | 0.80 | CHRM5 (0.47) | ACHEGALR3CHRM5CHRM1CHRM3 | |
| SCHEMBL28589432 | 0.80 | TSHR (0.51) | BBOX1ACHEGALR3CHRM5CHRM1 | |
| Sulfuric Acid SCHEMBL6473148 | 0.80 | TSHR (0.50) | BBOX1ACHEGALR3CHRM5CHRM1 | |
| Bromide SCHEMBL4884844 | 0.79 | GALR3 (0.48) | ACHEGALR3CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL737407 | 0.79 | CHRM5 (0.48) | GALR3CHRM5CHRM1CHRM3PGR | |
| SCHEMBL4460150 | 0.78 | CHRM5 (0.53) | ACHEGALR3CHRM5CHRM1CHRM3 | |
| SCHEMBL28745562 | 0.77 | ACHE (0.36) | BBOX1ACHEGALR3CHRM5CHRM1 | |
| SCHEMBL7033766 | 0.76 | TSHR (0.46) | BBOX1ACHEGALR3CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110402258-A | Actinic-radiation curable composition, solidfied material and film | DAINIPPON INK & CHEMICALS | 2019-11-01 | — | — | CN | disclosed |
| CN-109328198-A | Actinic-radiation curable composition and the film for using it | DIC株式会社 | 2019-02-12 | — | — | CN | disclosed |
| CN-109312012-A | Actinic-radiation curable composition and the film for using it | DIC株式会社 | 2019-02-05 | — | — | CN | disclosed |