Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 5/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | ACVR2A | P27037 | 4/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 3/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594646 | 0.79 | PIM1 (0.66) | FYNPIK3CGTGFBR2PIM1PIM2 | |
| SCHEMBL4327440 | 0.78 | FYN (0.52) | FYNPIK3CGMAPTSMN1; SMN2LMNA | |
| SCHEMBL4332430 | 0.76 | SCN5A (0.50) | PIM1PIM2RET | |
| SCHEMBL4335371 | 0.76 | FYN (0.59) | FYNPIK3CGMAPTSMN1; SMN2LMNA | |
| SCHEMBL4333317 | 0.75 | MAPT (0.57) | FYNPIK3CGMAPTSMN1; SMN2LMNA | |
| SCHEMBL4334657 | 0.74 | FYN (0.66) | FYNPIK3CGTGFBR2PIM1PIM2 | |
| SCHEMBL4595051 | 0.73 | PIK3CG (0.70) | FYNPIK3CGMAPTSMN1; SMN2LMNA | |
| Ammonia Solution, Strong SCHEMBL4594648 | 0.73 | FYN (0.61) | FYNPIK3CGMAPTSMN1; SMN2LMNA | |
| SCHEMBL4836241 | 0.72 | FYN (0.60) | FYNPIK3CGMAPTSMN1; SMN2LMNA | |
| SCHEMBL4325907 | 0.71 | PIK3CG (0.64) | FYNPIK3CGMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039455-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039455-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME | DPYD, FLT1, PDXK | FYN 151/4885PIK3CG 756/4885MAPT 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.