Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797576 | 0.73 | KDM4E (0.50) | KMT2APOLBMEN1ALDH1A1NPC1 | |
| SCHEMBL15254256 | 0.65 | HCAR3 (0.41) | PIM1 | |
| SCHEMBL23255570 | 0.62 | FYN (0.53) | KMT2APOLBMEN1ALDH1A1GAA | |
| SCHEMBL4784311 | 0.62 | ALDH1A1 (0.39) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL1240317 | 0.61 | CA12 (0.47) | ALDH1A1RAB9AKDM4ELMNAMAPK1 | |
| Octane SCHEMBL4474706 | 0.61 | EPHX1 (0.46) | ALDH1A1 | |
| SCHEMBL19182625 | 0.61 | TLR8 (0.44) | — | |
| SCHEMBL4850834 | 0.60 | GAA (0.42) | KMT2APOLBMEN1ALDH1A1GAA | |
| SCHEMBL9512936 | 0.60 | ABL1 (0.47) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL31497267 | 0.60 | THRA (0.53) | POLBALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069500-A1 | TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | disclosed |