Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885920 | 0.87 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL1680662 | 0.82 | MLYCD (0.51) | CYP1A2CYP2C19ALDH1A1MAPTLMNA | |
| SCHEMBL4875683 | 0.73 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL29924283 | 0.68 | RHEB (0.52) | CYP1A2CYP2C9CYP2C19ALDH1A1RHEB | |
| SCHEMBL6206121 | 0.68 | RHEB (0.52) | CYP1A2CYP2C9CYP2C19ALDH1A1RHEB | |
| SCHEMBL2096242 | 0.67 | WDR5 (0.59) | WDR5FKBP1ACYP2D6KMT2ALMNA | |
| SCHEMBL7370543 | 0.67 | MEN1 (0.58) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL16890555 | 0.66 | RHEB (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1RHEB | |
| SCHEMBL1680970 | 0.66 | SLC8A1 (0.53) | CYP1A2CYP2C19ALDH1A1MAPTLMNA | |
| SCHEMBL2667405 | 0.66 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19L3MBTL1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | PAH, TST, MPST | CYP1A2 1346/4885CYP2C9 1002/4885CYP2C19 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.