Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GRK2 | P25098 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886195 | 1.00 | PRKCI (0.36) | PRKCIDYRK1APIK3CADYRK2DYRK1B | |
| SCHEMBL4886190 | 1.00 | PRKCI (0.36) | PRKCIDYRK1APIK3CADYRK2DYRK1B | |
| SCHEMBL17032981 | 0.79 | KDM1A (0.44) | PRKCIDYRK1APIK3CADYRK2DYRK1B | |
| SCHEMBL4890839 | 0.77 | HTR3A (0.36) | SLC6A4HTR1AADRA2CCNR1SLC6A2 | |
| SCHEMBL4890857 | 0.77 | HTR3A (0.36) | SLC6A4HTR1AADRA2CCNR1SLC6A2 | |
| SCHEMBL4890845 | 0.77 | HTR3A (0.36) | SLC6A4HTR1AADRA2CCNR1SLC6A2 | |
| SCHEMBL2711041 | 0.77 | QDPR (0.47) | PRKCIDYRK1APIK3CAHTR6SIGMAR1 | |
| SCHEMBL18590462 | 0.73 | PDE4A (0.56) | PRKCIDYRK1APIK3CADYRK2DYRK1B | |
| SCHEMBL26513787 | 0.72 | HTR2C (0.41) | HTR2AHTR2BP2RY14 | |
| SCHEMBL25320358 | 0.71 | L3MBTL1 (0.43) | PRKCIDYRK1APIK3CADYRK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | PRKCI 3224/4885DYRK1A 3653/4885PIK3CA 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.