Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886196 | 1.00 | HDAC1 (0.43) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4015542 | 0.87 | HDAC3 (0.43) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4015537 | 0.87 | HDAC3 (0.43) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4887101 | 0.77 | HDAC1 (0.52) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4887097 | 0.77 | HDAC1 (0.52) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29169246 | 0.76 | GLA (0.36) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29169282 | 0.76 | GLA (0.36) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1619805 | 0.75 | ACACB (0.70) | ACACBCYP2C9ACACACYP2C19 | |
| SCHEMBL31139877 | 0.75 | POLB (0.48) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1619812 | 0.75 | ACACB (0.70) | ACACBCYP2C9ACACACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267942-A1 | BENZAZEPIN-2(1H)-ONE DERIVATIVES | PFIZER LIMITED (GB) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267942-A1 | BENZAZEPIN-2(1H)-ONE DERIVATIVES | ADRB2, ADRB1, ADRA2C | HDAC1 1362/4885HDAC2 250/4885HDAC3 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.