Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912015 | 0.88 | TRPM8 (0.56) | TRPM8KDM4EHSD17B10TSHRRECQL | |
| SCHEMBL4883688 | 0.88 | TRPM8 (0.56) | TRPM8KDM4EHSD17B10TSHRRECQL | |
| SCHEMBL4963208 | 0.85 | TRPM8 (0.64) | TRPM8KDM4ETSHRTDP1SMN1; SMN2 | |
| SCHEMBL10072942 | 0.85 | TRPM8 (0.64) | TRPM8KDM4ETSHRTDP1SMN1; SMN2 | |
| SCHEMBL2628761 | 0.83 | TRPM8 (0.58) | TRPM8ALDH1A1HPGDL3MBTL1P2RX4 | |
| SCHEMBL2628773 | 0.83 | TRPM8 (0.58) | TRPM8ALDH1A1HPGDP2RX4 | |
| SCHEMBL4812089 | 0.83 | P2RX4 (0.61) | TRPM8ALDH1A1HPGDNPSR1P2RX4 | |
| SCHEMBL2628771 | 0.82 | TRPM8 (0.57) | TRPM8TSHRALDH1A1NPSR1POLB | |
| SCHEMBL9950341 | 0.82 | ALDH1A1 (0.55) | KDM4EHSD17B10TSHRRECQLALDH1A1 | |
| SCHEMBL2580705 | 0.82 | ALDH1A1 (0.60) | KDM4EHSD17B10TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300314-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300314-A1 | Cooling Compounds | TAS2R42, TAS2R4, TAS2R41 | TRPM8 73/4885KDM4E 3399/4885HSD17B10 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.