Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | PKM | P14618 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728088 | 0.81 | RAB9A (0.61) | ALDH1A3ALDH1A1NPC1RAB9APKM | |
| SCHEMBL14260024 | 0.81 | APP (0.56) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL4779896 | 0.81 | APP (0.52) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL1691846 | 0.78 | NPC1 (0.68) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL4728696 | 0.78 | KDM4E (0.48) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL4729886 | 0.76 | APP (0.64) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL13325714 | 0.74 | RAB9A (0.69) | ALDH1A3ALDH1A1ALDH1A2NPC1RAB9A | |
| SCHEMBL1472271 | 0.74 | NPC1 (0.63) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL13325752 | 0.73 | SMN1; SMN2 (0.70) | ALDH1A1NPC1RAB9APKMKDM4E | |
| SCHEMBL13325743 | 0.72 | RAB9A (0.68) | ALDH1A1NPC1RAB9APKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |