Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | UTRN | P46939 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842127 | 0.82 | ALDH1A1 (0.57) | KDM4ELMNAHDAC6ALDH1A1NPC1 | |
| SCHEMBL4727646 | 0.81 | NPC1 (0.61) | KDM4EHDAC6ALDH1A1NPC1HPGD | |
| SCHEMBL1691846 | 0.78 | NPC1 (0.68) | KDM4ELMNAALDH1A1NPC1HPGD | |
| SCHEMBL4886789 | 0.78 | ALDH1A3 (0.43) | KDM4ELMNAALDH1A1NPC1HPGD | |
| SCHEMBL4729886 | 0.76 | APP (0.64) | KDM4ELMNACYP1A2ALDH1A1NPC1 | |
| SCHEMBL3739961 | 0.75 | CA1 (0.64) | KDM4ELMNAHDAC6CYP1A2AHR | |
| SCHEMBL13325714 | 0.74 | RAB9A (0.69) | KDM4ELMNAALDH1A1NPC1HPGD | |
| SCHEMBL1472271 | 0.74 | NPC1 (0.63) | KDM4ELMNAALDH1A1NPC1HPGD | |
| SCHEMBL4726593 | 0.72 | ALDH1A1 (0.74) | KDM4ECYP1A2UTRNALDH1A1NPC1 | |
| SCHEMBL13325743 | 0.72 | RAB9A (0.68) | KDM4EHDAC6ALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |