SCHEMBL4886989

SCHEMBL4886989

CCOc1cc(B(c2cc(OCC)c(Br)cc2Br)c2cc(OCC)c(Br)cc2Br)c(Br)cc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
HSD17B10 Q99714 3/20 0.41
TSHR P16473 1/20 0.41
HPGD P15428 3/20 0.39
MAPT P10636 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
POLB P06746 3/20 0.35
MAPK1 P28482 2/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10967724 0.80 LMNA (0.57) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL28060770 0.74 LMNA (0.47) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL16431851 0.71 HSD17B10 (0.48) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL19777817 0.71 LMNA (0.48) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL12187513 0.71 LMNA (0.63) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL27082761 0.71 L3MBTL1 (0.45) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL23326296 0.69 LMNA (0.52) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL19777872 0.69 LMNA (0.52) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL29775469 0.69 LMNA (0.52) LMNAHSD17B10TSHRHPGDMAPT
SCHEMBL7797947 0.69 LMNA (0.66) LMNAHSD17B10TSHRHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817318-B1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS NIPPON CATALYTIC CHEM IND (JP) 2013-08-28 EP disclosed
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds NIPPON SHOKUBAI CO., LTD. (JP) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds AR, AHR, BCL6 LMNA 2555/4885HSD17B10 1684/4885TSHR 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.