Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4887364 | 0.81 | L3MBTL1 (0.51) | ALDH1A1HTTKDM4EPKML3MBTL1 | |
| SCHEMBL4616279 | 0.80 | NPC1 (0.61) | L3MBTL1 | |
| SCHEMBL6419192 | 0.79 | CYP3A4 (0.62) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4888821 | 0.77 | L3MBTL1 (0.57) | ALDH1A1HTTKDM4EPKML3MBTL1 | |
| SCHEMBL4617266 | 0.77 | CYP3A4 (0.64) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4884427 | 0.77 | HTT (0.43) | ALDH1A1HTTKDM4EPKML3MBTL1 | |
| SCHEMBL4615852 | 0.74 | L3MBTL1 (0.64) | ALDH1A1HTTKDM4EPKML3MBTL1 | |
| SCHEMBL513356 | 0.73 | L3MBTL1 (0.64) | ALDH1A1HTTKDM4EPKML3MBTL1 | |
| SCHEMBL11741940 | 0.70 | MEN1 (0.67) | ALDH1A1HTTL3MBTL1 | |
| SCHEMBL11567450 | 0.69 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150201622-A1 | NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | CTT GROUP INC (CA) | 2015-07-23 | — | — | US | claimed |
| EP-1976388-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2008-10-08 | — | — | EP | claimed |
| US-20080199502-A1 | Antimicrobial Solution Comprising a Metallic Salt and a Surfactant | CTT GROUP INC. (CA) | 2008-08-21 | — | — | US | claimed |
| WO-2006105669-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2006-10-12 | — | — | WO | claimed |
| US-20150201622-A1 | NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | CTT GROUP INC (CA) | 2015-07-23 | — | — | US | disclosed |
| EP-1976388-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2008-10-08 | — | — | EP | disclosed |
| US-20080199502-A1 | Antimicrobial Solution Comprising a Metallic Salt and a Surfactant | CTT GROUP INC. (CA) | 2008-08-21 | — | — | US | disclosed |
| WO-2006105669-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2006-10-12 | — | — | WO | disclosed |