Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4887364

O=c1sc2ccccc2n1C[N+](CCO)(CCO)CCO.[Cl-]

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.51
KDM4E B2RXH2 1/20 0.51
PKM P14618 1/20 0.51
HTT P42858 1/20 0.51
TSHR P16473 2/20 0.48
MAPK1 P28482 2/20 0.48
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4914610 0.85 L3MBTL1 (0.51) L3MBTL1KDM4EPKMHTTTSHR
Hydrochloric Acid SCHEMBL4887877 0.81 ALDH1A1 (0.47) L3MBTL1KDM4EPKMHTTALDH1A1
Hydrochloric Acid SCHEMBL4888821 0.78 L3MBTL1 (0.57) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL4614755 0.78 L3MBTL1 (0.69) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL10831761 0.77 L3MBTL1 (0.64) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL4230610 0.75 L3MBTL1 (0.65) L3MBTL1HTTSMN1; SMN2NPC1RAB9A
SCHEMBL11350777 0.72 L3MBTL1 (0.66) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL11348784 0.72 L3MBTL1 (0.60) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL2149118 0.72 L3MBTL1 (0.53) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL2149124 0.72 L3MBTL1 (0.53) L3MBTL1KDM4EPKMHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150201622-A1 NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF CTT GROUP INC (CA) 2015-07-23 US claimed
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP claimed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US claimed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO claimed
US-20150201622-A1 NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF CTT GROUP INC (CA) 2015-07-23 US disclosed
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP disclosed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US disclosed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO disclosed