Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474593 | 0.85 | NOS3 (0.52) | NOS3NOS1NOS2TSHRALDH1A1 | |
| SCHEMBL29492839 | 0.85 | NOS3 (0.52) | NOS3NOS1NOS2TSHRALDH1A1 | |
| SCHEMBL8564866 | 0.82 | EGFR (0.41) | TSHRALDH1A1CYP3A4RECQLTDP1 | |
| SCHEMBL3360541 | 0.80 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4RECQLGAA | |
| SCHEMBL2669593 | 0.77 | TSHR (0.43) | TSHRALDH1A1CYP3A4RECQLGAA | |
| SCHEMBL2914482 | 0.77 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL31481315 | 0.77 | GPR35 (0.47) | TSHRALDH1A1CYP3A4RECQLGAA | |
| SCHEMBL16663608 | 0.77 | ALDH1A1 (0.49) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL30749766 | 0.77 | TSHR (0.43) | TSHRALDH1A1CYP3A4RECQLGAA | |
| SCHEMBL13470589 | 0.77 | CYP1A2 (0.47) | TSHRALDH1A1CYP3A4RECQLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9177773-B2 | Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum | WAYNE STATE UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| US-9177773-B2 | Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum | WAYNE STATE UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150053854-A1 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2015-02-26 | — | — | US | disclosed |
| US-20150053854-A1 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2015-02-26 | — | — | US | disclosed |
| US-8853621-B2 | Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum | WAYNE STATE UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20140027631-A1 | Systems and Methods Extending the Laserspray Ionization Mass Spectrometry Concept from Atmospheric Pressure to Vacuum | WAYNE STATE UNIVERSITY (US) | 2014-01-30 | — | — | US | disclosed |
| EP-1840122-B1 | AMINOPYRIMIDINE COMPOUNDS AND THEIR SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL USE THEREOF | SUN PIAOYANG (CN) | 2013-08-28 | — | — | EP | disclosed |
| US-8183242-B2 | Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof | Sun, Piaoyang (CN) | 2012-05-22 | — | — | US | disclosed |
| WO-2012058248-A2 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2012-05-03 | — | — | WO | disclosed |
| CN-1972917-B | Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof | PIAOYANG SUN | 2010-08-25 | — | — | CN | disclosed |
| US-20080312251-A1 | Aminopyrimidine Compounds and Their Salts, Process for Preparation and Pharmaceutical Use Thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2008-12-18 | — | — | US | disclosed |
| EP-1840122-A1 | AMINOPYRIMIDINE COMPOUNDS AND THEIR SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL USE THEREOF | Sun, Piaoyang (CN) | 2007-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312251-A1 | Aminopyrimidine Compounds and Their Salts, Process for Preparation and Pharmaceutical Use Thereof | DPYD, PKN2, TYMP | NOS3 2333/4885NOS1 1769/4885NOS2 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.