SCHEMBL4888912

SCHEMBL4888912

Cc1ccc(C23C=CC(C(=O)c4ccccc4)=CC2S3)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
AKR1C3 P42330 1/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
PTGS2 P35354 1/20 0.35
ALDH1A1 P00352 6/20 0.34
MAPT P10636 5/20 0.34
HPGD P15428 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 3/20 0.34
SRD5A2 P31213 1/20 0.34
CCR2 P41597 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.33
POLB P06746 1/20 0.33
GLA P06280 1/20 0.32
TNNI3 P19429 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28361882 0.79 CES2 (0.40) CES2CES1AKR1C3MEN1KMT2A
SCHEMBL28395045 0.78 CCR2 (0.33) NPC1RAB9AMAPTTDP1LMNA
SCHEMBL29183161 0.75 ALDH1A1 (0.38) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL28491481 0.66
SCHEMBL11227122 0.65 ALDH1A1 (0.39) AKR1C3MEN1KMT2ANPC1RAB9A
SCHEMBL28552569 0.65 ALDH1A1 (0.39) AKR1C3MEN1KMT2ANPC1RAB9A
SCHEMBL30065188 0.65 EZH2 (0.38) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL235 0.65 ALDH1A1 (0.80) CES2CES1AKR1C3MEN1KMT2A
Benzophenone SCHEMBL5162782 0.65 ALDH1A1 (0.80) CES2CES1AKR1C3MEN1KMT2A
SCHEMBL259065 0.65 ALDH1A1 (0.80) CES2CES1AKR1C3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080176169-A1 BINDER COMPOSITION AND PHOTOSENSITIVE COMPOSITION INCLUDING THE SAME ICF TECHNOLOGY LIMITED. (US) 2008-07-24 US claimed
CN-103901718-A Photosensitive Resin Composition for Color Filter and Color Filter Using the Same CHEIL IND INC 2014-07-02 CN disclosed
US-20080176169-A1 BINDER COMPOSITION AND PHOTOSENSITIVE COMPOSITION INCLUDING THE SAME ICF TECHNOLOGY LIMITED. (US) 2008-07-24 US disclosed