SCHEMBL4889235

SCHEMBL4889235

CC(N)N(CCO)CCO

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326627 0.75 MAPT (0.42) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL79660 0.75 MAPT (0.42) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL2020312 0.74
SCHEMBL7108229 0.74 TSHR (0.38) MAPTALDH1A1TSHR
SCHEMBL16403673 0.73 ALDH1A1 (0.37) ALDH1A1
Trolamine SCHEMBL28683075 0.73 MAPT (0.40) MAPTALDH1A1TSHR
Water SCHEMBL3302021 0.73 MAPT (0.40) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL1626524 0.73 FDPS (0.39) ALDH1A1
SCHEMBL2058214 0.73 MAPT (0.40) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL12790540 0.73 MAPT (0.40) MAPTMEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0207864-B1 BINDERS FOR MANUFACTURE OF PRECISION CASTING MOLDS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-05-08 EP claimed
EP-0255441-B1 BINDER FOR MANUFACTURE OF PRECISION CASTING MOLD NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-04-11 EP claimed
EP-1280880-B1 LAUNDRY DETERGENT COMPOSITIONS CONTAINING A POLYMER PROCTER & GAMBLE (US) 2008-10-29 EP disclosed
US-20080249279-A1 Acid Groups-Containing Polyurethane Resins CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) 2008-10-09 US disclosed
EP-1645581-A1 Polyurethane resins containing acid groups Cytec Surface Specialties Austria GmbH (AT) 2006-04-12 EP disclosed
EP-1325107-B1 LAUNDERING AID FOR PREVENTING DYE TRANSFER PROCTER & GAMBLE (US) 2005-08-03 EP disclosed
US-6887524-B2 Method for manufacturing laundry additive article THE PROCTER & GAMBLE COMPANY (US) 2005-05-03 US disclosed
US-6833336-B2 To remove extraneous dyes from a wash solution before redeposition onto other articles and/or garments can occur THE PROCTER & GAMBLE COMPANY 2004-12-21 US disclosed
US-6740633-B2 Polyelectrolyte complexes and a method for production thereof BASF AKTIENGESELLSCHAFT (DE) 2004-05-25 US disclosed
US-20030220365-A1 Cell adhesion-inhibiting antiinflammatory compounds STEWART ANDREW O (US) 2003-11-27 US disclosed
US-20030158075-A1 Laundering aid for preventing dye transfer THE PROCTER & GAMBLE COMPANY 2003-08-21 US disclosed
US-5516758-A Polyamides bearing functionalized side chains useful as water soluble hypolipidemic agents BERLEX LABORATORIES, INC. (US) 1996-05-14 US disclosed
EP-0389079-B1 Polyamides bearing functionalized side chains useful as water soluble hypolipidemic agents BERLEX LAB (US) 1995-04-19 EP disclosed
EP-0519119-A1 Polyamides bearing functionalized side chains useful as water soluble hypolipidemic agents BERLEX LABORATORIES, INC. (US) 1992-12-23 EP disclosed
EP-0389079-A2 Polyamides bearing functionalized side chains useful as water soluble hypolipidemic agents BERLEX LABORATORIES, INC. (US) 1990-09-26 EP disclosed
WO-1989011870-A1 USE OF SPECIAL AMINES TO PREVENT NITROSAMINE FORMATION MERCK PATENT GMBH (DE) 1989-12-14 WO disclosed
EP-0344564-A1 Utilisation of special amines or hindering nitrosamine production Eisenbrand, Gerhard, Prof. Dr. (DE) 1989-12-06 EP disclosed
EP-0145226-B1 SUBSTITUTED 1-AMINO-4-NITRO-ACRIDINONES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND PROCESSES FOR THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1988-10-05 EP disclosed
US-4626540-A Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them WARNER-LAMBERT COMPANY (US) 1986-12-02 US disclosed
EP-0145226-A2 Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production WARNER-LAMBERT COMPANY (US) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220365-A1 Cell adhesion-inhibiting antiinflammatory compounds ICAM1, VCAM1, EPCAM MAPT 3906/4885MEN1 4064/4885KMT2A 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.