Sugi Predict

Sugi Predict / Compounds / SCHEMBL4889617

SCHEMBL4889617

SCHEMBL4889617

CC(C)(C)Oc1ccc2c(c1)Cc1cc(OC(C)(C)C)ccc1-2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ METAP1 P53582 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ KIF11 P52732 1/20 0.40
▸ NPC1 O15118 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ DRD2 P14416 3/20 0.38
▸ DRD1 P21728 3/20 0.38
▸ DRD5 P21918 3/20 0.38
▸ DRD3 P35462 3/20 0.38
▸ CYP19A1 P11511 2/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ CASP6 P55212 1/20 0.35
▸ GFER P55789 1/20 0.35
▸ KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24517924 0.89 ALDH1A1 (0.39) METAP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL4892661 0.88 METAP1 (0.40) METAP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL21217282 0.81 DRD1 (0.41) ALOX15HSD17B10KIF11DRD2DRD1
SCHEMBL29308777 0.79 CYP1A2 (0.40) METAP1CYP1A2CYP3A4CYP2C9KIF11
SCHEMBL18355358 0.78 STS (0.46) ALDH1A1ALOX15HSD17B10NPC1RAB9A
SCHEMBL20456250 0.78 STS (0.50) ALDH1A1ALOX15HSD17B10KIF11NPC1
SCHEMBL30777630 0.76 METAP1 (0.63) METAP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL4581239 0.76 METAP1 (0.63) METAP1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL22871054 0.75 KIF11 (0.40) ALDH1A1KIF11NPC1MAPTRAB9A
SCHEMBL29326125 0.75 MAPT (0.41) ALDH1A1KIF11NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084559-B2 Ethylene-vinylcyclohexane copolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-27 — — US disclosed
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2008-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer AOC2, ACSL1, ACSL3 METAP1 2844/4885ALDH1A1 1292/4885CYP1A2 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.