Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 5/20 | 0.38 |
| ▸ | CA6 | P23280 | 5/20 | 0.38 |
| ▸ | CA5A | P35218 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.38 |
| ▸ | CA3 | P07451 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48888 | 0.80 | TMPRSS11D (0.44) | F10PLG | |
| SCHEMBL49083 | 0.75 | TMPRSS11D (0.49) | F10PRSS1ITGB3ITGA2BPLG | |
| SCHEMBL28848539 | 0.74 | MMP2 (0.46) | CA12CA1CA2NPY1RNPY2R | |
| SCHEMBL28848545 | 0.71 | NPY4R (0.55) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL31122216 | 0.71 | OPRD1 (0.49) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29630726 | 0.69 | OPRD1 (0.51) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7530381 | 0.69 | MMP2 (0.48) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7530376 | 0.69 | MMP2 (0.48) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL7416564 | 0.69 | MMP2 (0.48) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL6864434 | 0.69 | HPGD (0.46) | ITGB3ITGA2BNPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129547-B2 | Anticoagulation of human blood ex vivo | HELLSTERN PETER (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20100280412-A1 | Anticoagulation Of Human Blood Ex Vivo | HELLSTERN PETER | 2010-11-04 | — | — | US | disclosed |
| EP-1973929-B1 | ANTICOAGULATION OF HUMAN BLOOD EX VIVO | HELLSTERN PETER (DE) | 2010-09-29 | — | — | EP | disclosed |
| EP-1973929-A2 | ANTICOAGULATION OF HUMAN BLOOD EX VIVO | Hellstern, Peter (DE) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007085461-A2 | ANTICOAGULATION OF HUMAN BLOOD EX VIVO | STÜRZEBECHER, Uta (DE) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280412-A1 | Anticoagulation Of Human Blood Ex Vivo | F5, TFPI, F11 | CA12 117/4885CA1 76/4885CA2 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.