Cadaverine Tartrate — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CHRM1 CHRM2 CHRM3 CHRM4 ESR1 ESR2 GABRA1 GABRB1 GABRG2 GBA1 HRH1 HTR1D HTR2A OPRD1 OPRK1 OPRM1 SLC6A2 SLC6A3 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1 known ✓	P35372	1/20	0.54

▸	GABRA1 known ✓	P14867	2/20	0.45

▸	GABRB1 known ✓	P18505	2/20	0.45

▸	GABRG2 known ✓	P18507	2/20	0.45

▸	TP53	P04637	1/20	0.53

▸	SLC1A2	P43004	2/20	0.48

▸	SLC1A1	P43005	2/20	0.48

▸	SLC1A3	P43003	1/20	0.48

▸	CA2	P00918	2/20	0.47

▸	MAPK1	P28482	1/20	0.47

▸	GPR84	Q9NQS5	3/20	0.45

▸	FFAR1	O14842	1/20	0.45

▸	GABRP	O00591	2/20	0.45

▸	GABRD	O14764	2/20	0.45

▸	GABRB3	P28472	2/20	0.45

▸	GABRA5	P31644	2/20	0.45

▸	GABRA3	P34903	2/20	0.45

▸	GABRA2	P47869	2/20	0.45

▸	GABRB2	P47870	2/20	0.45

▸	GABRA4	P48169	2/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Bicarbonate SCHEMBL6548682	0.87	OPRM1 (0.64)	OPRM1TP53SLC1A2SLC1A1SLC1A3
Acetic Acid SCHEMBL5571311	0.85	OPRM1 (0.61)	OPRM1TP53SLC1A2SLC1A1SLC1A3
Oxalic Acid SCHEMBL28713733	0.85	OPRM1 (0.61)	OPRM1TP53SLC1A2SLC1A1SLC1A3
Oxalic Acid SCHEMBL28713732	0.85	OPRM1 (0.61)	OPRM1TP53SLC1A2SLC1A1SLC1A3
Lactic Acid SCHEMBL5574449	0.82	OPRM1 (0.64)	OPRM1TP53SLC1A2SLC1A1GPR84
SCHEMBL10310671	0.81	SLC1A2 (0.50)	TP53SLC1A2SLC1A1SLC1A3CA2
SCHEMBL8016824	0.81	SLC1A2 (0.50)	TP53SLC1A2SLC1A1SLC1A3CA2
SCHEMBL8283884	0.81	SLC1A2 (0.50)	TP53SLC1A2SLC1A1SLC1A3CA2
Tuaminoheptane SCHEMBL25287775	0.80	OPRM1 (0.76)	OPRM1TP53SLC1A2SLC1A1GPR84
Tuaminoheptane SCHEMBL3365884	0.80	OPRM1 (0.76)	OPRM1TP53SLC1A2SLC1A1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20080194696-A1	Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use	ETHISMOS RESEARCH, INC.	2008-08-14	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20080194696-A1	Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use	HTR2C, HTR1B, HTR3C	OPRM1 91/4885GABRA1 252/4885GABRB1 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.