Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862962 | 0.79 | NSD2 (0.49) | ALDH1A1KDM4ETSHRNPC1RECQL | |
| SCHEMBL27727791 | 0.74 | HCAR3 (0.48) | ALDH1A1KDM4ETSHRNPC1RAB9A | |
| SCHEMBL3354917 | 0.73 | HSD17B10 (0.48) | ALDH1A1TSHRNPC1RECQLRAB9A | |
| SCHEMBL10618157 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4ETSHRTDP1GPR35 | |
| SCHEMBL9777370 | 0.70 | GPR35 (0.38) | ALDH1A1TSHRNPC1RECQLRAB9A | |
| SCHEMBL3655437 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1RECQLRAB9A | |
| SCHEMBL11293523 | 0.69 | PDK1 (0.43) | ALDH1A1TSHRHTTTDP1GPR35 | |
| SCHEMBL8893719 | 0.69 | KDM4E (0.44) | ALDH1A1KDM4ETSHRRAB9ATDP1 | |
| SCHEMBL11509787 | 0.69 | KMT2A (0.42) | ALDH1A1KDM4ETSHRHTTTDP1 | |
| SCHEMBL11565380 | 0.68 | HSD17B10 (0.52) | ALDH1A1TSHRNPC1RECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7431741-B2 | Brightening colorant with indolythiazolium dyes | WELLA AG (DE) | 2008-10-07 | — | — | US | disclosed |
| US-20070180631-A1 | Brightening colorant with indolythiazolium dyes | Wella GmbH (DE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070180631-A1 | Brightening colorant with indolythiazolium dyes | KRT18, TUBB1, IK | ALDH1A1 89/4885KDM4E 997/4885TSHR 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.