Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447142 | 0.78 | CTNNB1 (0.41) | CYP1A2CYP2C19CYP2D6ALDH1A1LMNA | |
| SCHEMBL6447751 | 0.76 | CTNNB1 (0.42) | CYP1A2CYP2C19CYP2D6ALDH1A1LMNA | |
| SCHEMBL31258909 | 0.75 | ATM (0.50) | CYP1A2CYP2C19CYP2D6CYP2C9SIGMAR1 | |
| SCHEMBL11214375 | 0.75 | ATM (0.50) | CYP1A2CYP2C19CYP2D6CYP2C9SIGMAR1 | |
| SCHEMBL7296607 | 0.75 | CTNNB1 (0.41) | CYP1A2CYP2C19CYP2D6ALDH1A1LMNA | |
| SCHEMBL1823898 | 0.74 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2D6ALDH1A1LMNA | |
| SCHEMBL10389712 | 0.74 | CTNNB1 (0.50) | CYP1A2CTSSCTSKCTNNB1KMT2A | |
| SCHEMBL27627250 | 0.73 | CYP1A2 (0.46) | CYP1A2CYP2C19CYP2D6ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10433751 | 0.72 | SIGMAR1 (0.44) | CYP1A2CYP2C19CYP2D6CYP2C9SIGMAR1 | |
| SCHEMBL10390136 | 0.72 | CTSS (0.44) | CYP1A2CYP2D6ALDH1A1HPGDCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976388-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2008-10-08 | — | — | EP | claimed |
| US-20080199502-A1 | Antimicrobial Solution Comprising a Metallic Salt and a Surfactant | CTT GROUP INC. (CA) | 2008-08-21 | — | — | US | claimed |
| WO-2006105669-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2006-10-12 | — | — | WO | claimed |
| US-20150201622-A1 | NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | CTT GROUP INC (CA) | 2015-07-23 | — | — | US | disclosed |
| EP-1976388-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2008-10-08 | — | — | EP | disclosed |
| US-20080199502-A1 | Antimicrobial Solution Comprising a Metallic Salt and a Surfactant | CTT GROUP INC. (CA) | 2008-08-21 | — | — | US | disclosed |
| WO-2006105669-A1 | ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT | CTT GROUP INC. (CA) | 2006-10-12 | — | — | WO | disclosed |