Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Alcohol SCHEMBL5039741 | 0.91 | TSHR (0.61) | TSHRPPARGPPARALTA4HTDP1 | |
| Methacrylic Acid SCHEMBL9618253 | 0.88 | TSHR (0.50) | TSHRLTA4HKMT2ALMNABAZ2B | |
| Methacrylic Acid SCHEMBL27884246 | 0.87 | MAPT (0.53) | PPARGPPARACA1CA2LTA4H | |
| Methacrylic Acid SCHEMBL5685586 | 0.87 | ALDH1A1 (0.39) | TSHRPPARGPPARANOS3NOS1 | |
| Benzyl Alcohol SCHEMBL7200891 | 0.82 | TSHR (0.50) | TSHRPPARGPPARALTA4HCA12 | |
| Oxalic Acid SCHEMBL30089202 | 0.82 | TSHR (0.58) | TSHRPPARGPPARANOS3NOS1 | |
| SCHEMBL21840691 | 0.80 | THRA (0.59) | PPARGPPARANOS3NOS1CA1 | |
| Methacrylic Acid SCHEMBL11141850 | 0.77 | CYP4F2 (0.44) | TSHRCYP4F2CYP4A11TDP1KMT2A | |
| Acetic Acid SCHEMBL9299626 | 0.76 | SMN1; SMN2 (0.47) | TSHRPPARGPPARANOS3NOS1 | |
| Parahydroxybenzyl Alcohol SCHEMBL906796 | 0.76 | CA2 (0.54) | TSHRPPARGPPARACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814523-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING A MULTI-ARM PEG MACROMER | NOVARTIS AG (CH) | 2016-04-06 | — | — | EP | claimed |
| US-9012581-B2 | Ophthalmic and otorhinolaryngological device materials | NOVARTIS AG (CH) | 2015-04-21 | — | — | US | claimed |
| US-8900297-B2 | Ophthalmic and otorhinolaryngological device materials | NOVARTIS AG (CH) | 2014-12-02 | — | — | US | claimed |
| EP-2470578-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | NOVARTIS AG (CH) | 2014-11-12 | — | — | EP | claimed |
| US-20140213733-A1 | Ophthalmic and Otorhinolaryngological Device Materials | NOVARTIS AG (CH) | 2014-07-31 | — | — | US | claimed |
| US-8728157-B2 | Ophthalmic and otorhinolaryngological device materials | NOVARTIS AG (CH) | 2014-05-20 | — | — | US | claimed |
| US-20140024777-A1 | Ophthalmic And Otorhinolaryngological Device Materials Containing An Alkylphenol Ethoxylate | NOVARTIS AG (CH) | 2014-01-23 | — | — | US | claimed |
| US-8574292-B2 | Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate | NOVARTIS AG (CH) | 2013-11-05 | — | — | US | claimed |
| US-8293858-B1 | Ophthalmic and otorhinolaryngological device materials containing a reactive NVP macromer | NOVARTIS AG (CH) | 2012-10-23 | — | — | US | claimed |
| US-8163862-B2 | Ophthalmic and otorhinolaryngological device materials | NOVARTIS AG (CH) | 2012-04-24 | — | — | US | claimed |
| EP-2192930-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE | ALCON INC (CH) | 2011-04-13 | — | — | EP | claimed |
| US-20110046258-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2011-02-24 | — | — | US | claimed |
| US-7888403-B2 | soft foldable intraocular lenses with no glistenings or vacuoles when stored in water; monofunctional phenyl or alkylphenyl acrylate or acrylamide and difunctional acrylate or acrylamide monomers; a di- or tri-block acrylic macromer | ALCON, INC. (CH) | 2011-02-15 | — | — | US | claimed |
| US-7858672-B1 | Methacrylic materials suitable for ophthalmic and otorhinolaryngological devices | ALCON, INC. (CH) | 2010-12-28 | — | — | US | claimed |
| US-7799845-B2 | Ophthalmic and otorhinolaryngological device materials | ALCON, INC. (CH) | 2010-09-21 | — | — | US | claimed |
| US-20090093603-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | US | claimed |
| US-20090093604-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | US | claimed |
| US-20090093592-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | US | claimed |
| US-20090088544-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE | ALCON, INC. (CH) | 2009-04-02 | — | — | US | claimed |
| US-20090088493-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYLPHENOL ETHOXYLATE | ALCON, INC. (CH) | 2009-04-02 | — | — | US | claimed |