Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388035 | 0.96 | ALDH1A1 (0.40) | ALDH1A1GPR35TTRALBACHE | |
| SCHEMBL29556360 | 0.89 | ALDH1A1 (0.35) | ALDH1A1GPR35NCEH1MEN1KMT2A | |
| SCHEMBL17963944 | 0.89 | ALDH1A1 (0.35) | ALDH1A1GPR35NCEH1MEN1KMT2A | |
| SCHEMBL5784328 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2580324 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL24372708 | 0.80 | ALDH1A1 (0.49) | ALDH1A1ACHE | |
| SCHEMBL9351752 | 0.79 | GPR35 (0.36) | ALDH1A1GPR35TTRALBNCEH1 | |
| SCHEMBL12158729 | 0.79 | GPR35 (0.36) | ALDH1A1GPR35TTRALBNCEH1 | |
| SCHEMBL9352583 | 0.78 | NCEH1 (0.45) | ALDH1A1ACHENCEH1MEN1KMT2A | |
| SCHEMBL9495594 | 0.77 | MMP3 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | PFIZER INC. (US) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | SPR, TPMT, IMPDH1 | ALDH1A1 84/4885GPR35 3665/4885TTR 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.