SCHEMBL4891196

SCHEMBL4891196

C=C(CC)C(=O)O.O=C(O)C=CF

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HCAR2 Q8TDS4 2/20 0.33
TET2 Q6N021 5/20 0.32
TSHR P16473 3/20 0.32
TP53 P04637 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
EGLN3 Q9H6Z9 1/20 0.32
FFAR3 O14843 1/20 0.31
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL7518661 0.87 TSHR (0.45) ALOX15HSD17B10HCAR2TET2TSHR
Fumaric Acid SCHEMBL4270106 0.87 TSHR (0.45) ALOX15HSD17B10HCAR2TET2TSHR
Maleic Acid SCHEMBL7518651 0.87 TSHR (0.45) ALOX15HSD17B10HCAR2TET2TSHR
Maleic Acid SCHEMBL2213373 0.87 TSHR (0.45) ALOX15HSD17B10HCAR2TET2TSHR
Fumaric Acid SCHEMBL7520083 0.87 TSHR (0.45) ALOX15HSD17B10HCAR2TET2TSHR
Crotonic Acid SCHEMBL27711584 0.81 ALOX15 (0.39) ALOX15HSD17B10HCAR2TET2TSHR
Crotonic Acid SCHEMBL28123858 0.79 ALOX15 (0.38) ALOX15HSD17B10HCAR2TET2TSHR
SCHEMBL156659 0.79 FFAR3 (0.47) ALOX15HSD17B10TET2TSHRTP53
SCHEMBL17865 0.79
Acrylic Acid SCHEMBL28411354 0.78 ALOX15 (0.60) ALOX15HSD17B10TET2TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190320-A1 FUSER MEMBER XEROX CORPORATION (US) 2007-08-16 US claimed
US-8518476-B2 Methods for forming fluoroplastic powder coatings XEROX CORPORATION (US) 2013-08-27 US disclosed
US-20130115380-A1 METHODS FOR FORMING FLUOROPLASTIC POWDER COATINGS XEROX CORPORATION (US) 2013-05-09 US disclosed
US-7462395-B2 Fuser member XEROX CORPORATION (US) 2008-12-09 US disclosed
US-20070190320-A1 FUSER MEMBER XEROX CORPORATION (US) 2007-08-16 US disclosed