SCHEMBL1745006

SCHEMBL1745006

O=C(O)COc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 14/20 0.73
FFAR4 Q5NUL3 4/20 0.73
PPARG P37231 1/20 0.61
PPARD Q03181 1/20 0.61
ALOX15 P16050 1/20 0.59
PTPRC P08575 1/20 0.52
PTPN1 P18031 1/20 0.52
AKR1B1 P15121 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6239573 0.87 FFAR1 (0.76) FFAR1FFAR4AKR1B1
SCHEMBL9491438 0.86 FFAR1 (0.68) FFAR1FFAR4
SCHEMBL1745467 0.85 FFAR1 (1.00) FFAR1FFAR4AKR1B1
SCHEMBL9403761 0.84 LMNA (0.68) FFAR1FFAR4
SCHEMBL1115002 0.84 PPARG (0.71) FFAR1FFAR4PPARGPPARDALOX15
SCHEMBL5009454 0.84 ALOX15 (0.83) FFAR1FFAR4PPARGPPARDALOX15
SCHEMBL1746856 0.84 PPARD (0.81) FFAR1FFAR4PPARGPPARDAKR1B1
SCHEMBL6239576 0.83 FFAR1 (0.66) FFAR1FFAR4PPARGPTPRCPTPN1
SCHEMBL2774848 0.83 NR4A2 (0.66) FFAR1PPARGPPARDALOX15
SCHEMBL7521762 0.83 FFAR1 (0.58) FFAR1FFAR4PPARGALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1559422-B1 RECEPTOR FUNCTION CONTROLLING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-04-30 EP disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR FFAR1 33/4885FFAR4 44/4885PPARG 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.