Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894642 | 0.89 | HEXA (0.43) | L3MBTL1KMT2AMAPTMMP2MMP3 | |
| SCHEMBL4729932 | 0.82 | MAPK1 (0.39) | L3MBTL1KMT2ATDP1CYP2D6MAPK1 | |
| SCHEMBL4782265 | 0.74 | MAOB (0.41) | L3MBTL1RAB9AKMT2ATDP1ALDH1A1 | |
| SCHEMBL4569116 | 0.68 | RAB9A (0.74) | L3MBTL1RAB9AKMT2ATDP1MAPT | |
| SCHEMBL4891517 | 0.67 | L3MBTL1 (0.39) | L3MBTL1RAB9AKMT2ATDP1MAPT | |
| SCHEMBL15923064 | 0.65 | KMT2A (0.52) | L3MBTL1RAB9AKMT2ATDP1MAPT | |
| SCHEMBL15923238 | 0.65 | KMT2A (0.52) | L3MBTL1RAB9AKMT2ATDP1MAPT | |
| SCHEMBL674943 | 0.65 | CTSS (0.40) | RAB9AKMT2ATDP1MAPTTP53 | |
| SCHEMBL4729192 | 0.64 | OPRK1 (0.40) | KMT2AALDH1A1MAPK1MEN1 | |
| Dimethylamine SCHEMBL9872141 | 0.64 | RAB9A (0.63) | L3MBTL1RAB9AKMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242694-A1 | Amino-substituted heterocycles, compositions thereof, and methods of treatment therewith | D SIDOCKY NEIL R | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242694-A1 | Amino-substituted heterocycles, compositions thereof, and methods of treatment therewith | JAK2, CHEK2, MTOR | L3MBTL1 1483/4885RAB9A 2813/4885KMT2A 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.