Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903086 | 0.87 | PDE1A (0.40) | PDE1APDE1BPDE4D | |
| SCHEMBL6738331 | 0.72 | CYP1A1 (0.45) | PDE1APDE1BPDE4D | |
| Bromide SCHEMBL4939908 | 0.71 | CYP1A1 (0.46) | PDE1APDE1BPDE4D | |
| SCHEMBL3384380 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL3384385 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL963152 | 0.67 | CNR2 (0.33) | PDE1APDE1BPDE4D | |
| SCHEMBL2484586 | 0.59 | NOTUM (0.37) | — | |
| SCHEMBL963478 | 0.56 | TPH1 (0.31) | — | |
| SCHEMBL23749779 | 0.55 | ALDH1A1 (0.48) | PDE1APDE1B | |
| SCHEMBL945777 | 0.54 | KMT2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735434-B2 | Compounds as cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20080287510-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287510-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | PDE1A 975/4885PDE1B 708/4885PDE4D 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.