Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14087746 | 0.83 | L3MBTL1 (0.41) | SMN1; SMN2L3MBTL1ALDH1A1MAPTRECQL | |
| SCHEMBL14087761 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL14087759 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL21067812 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL4895027 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL14087809 | 0.78 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL4744922 | 0.78 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL4893496 | 0.78 | MAPT (0.41) | SMN1; SMN2L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL4896496 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL14087739 | 0.77 | KMT2A (0.44) | ALDH1A1KMT2AKDM4EPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | SMN1; SMN2 4735/4885L3MBTL1 3221/4885ALDH1A1 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.